3-[3-(2-DIMETHYLAMINOETHYL)-1H-INDOL-5-YL]-N-(4-METHOXYBENZYL)ACRYLAMIDE
3-[3-(2-DIMETHYLAMINOETHYL)-1H-INDOL-5-YL]-N-(4-METHOXYBENZYL)ACRYLAMIDE
CAS: 185259-85-2
Molecular Formula: C23H27N3O2
3-[3-(2-DIMETHYLAMINOETHYL)-1H-INDOL-5-YL]-N-(4-METHOXYBENZYL)ACRYLAMIDE - Names and Identifiers
| Name | 3-[3-(2-DIMETHYLAMINOETHYL)-1H-INDOL-5-YL]-N-(4-METHOXYBENZYL)ACRYLAMIDE |
| Synonyms | GR-46611 3-[3-(2-DIMETHYLAMINOETHYL)-1H-INDOL-5-YL]-N-(4-METHOXYBENZYL)ACRYLAMIDE |
| CAS | 185259-85-2 |
3-[3-(2-DIMETHYLAMINOETHYL)-1H-INDOL-5-YL]-N-(4-METHOXYBENZYL)ACRYLAMIDE - Physico-chemical Properties
| Molecular Formula | C23H27N3O2 |
| Molar Mass | 377.49 |
| Solubility | Ethanol: 5 mM;DMSO: 25 mM mother liquor preservation: sub-package and freeze storage to avoid repeated freezing and thawing;-20 ℃,1 month;-80 ℃,6 months (after dilution, the solution temperature is low and storage may precipitate, as far as possible with the current preparation) Cell experiment: dissolve with DMSO first, dilute with culture medium, and the dilution process is recommended to be carried out in stages to avoid the concentration change too fast leading to the precipitation of compounds. If the compound is precipitated during the dilution process, it can be redissolved by ultrasound. During dilution, ensure that the final concentration of DMSO in the working fluid should be below 0.1% as far as possible, and the maximum should not exceed 0.5%, and set up a DMSO control group with corresponding concentration. Animal experiment: Dissolve with DMSO first: dilute with water or normal saline, etc. The dilution process is recommended to be carried out in sections to avoid excess |
| Storage Condition | -20℃ |
| Use | GR-46611 is a 5-HT1D receptor agonist. |
3-[3-(2-DIMETHYLAMINOETHYL)-1H-INDOL-5-YL]-N-(4-METHOXYBENZYL)ACRYLAMIDE - Reference
| Reference Show more | 1. Clitherow et al (1994) Evolution of a novel series of [(N,N-Dimethylamino)propyl]- and piperazinylbenzanilides as the first selective 5-HT1D antagonists. J.Med.Chem. 37 2253 PMID: 80572722. Skingle et al (1994) Stimulation of central 5-HT1D receptors causes hypothermia in the guinea pig. J.Psychopharmacol. 8 14 |
3-[3-(2-DIMETHYLAMINOETHYL)-1H-INDOL-5-YL]-N-(4-METHOXYBENZYL)ACRYLAMIDE - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.649 ml | 13.245 ml | 26.491 ml |
| 5 mM | 0.53 ml | 2.649 ml | 5.298 ml |
| 10 mM | 0.265 ml | 1.325 ml | 2.649 ml |
| 5 mM | 0.053 ml | 0.265 ml | 0.53 ml |
Last Update：2024-01-02 23:10:35
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Product Name: 3-[3-(2-DIMETHYLAMINOETHYL)-1H-INDOL-5-YL]-N-(4-METHOXYBENZYL)ACRYLAMIDE Visit Supplier Webpage Request for quotation
CAS: 185259-85-2
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Mobile: 18021002903
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CAS: 185259-85-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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